McCoy, Isaac, missionary, was born near Uniontown, Fayette county, Pa., June 13, 1784. The next year his family removed to Kentucky; where his youth was passed, and in 1817 he began his work as a missionary among the Miami Indians in the Wabash valley in Indiana. In the spring of 1820 he went to Fort Wayne, Ind., and in Dec., 1822, followed the Pottawatomie Indians to Michigan, becoming the founder of the Grand river mission in 1826. Two years later he was one of the commissioners appointed to visit the western country and select homes for the Ottawas and Pottawatomies. In Jan., 1829, he visited Washington and made a report of his investigations, and in July he again started west. In 1837 he was sent by the government to survey the Delaware lands and while on this work he made arrangements for missions among the Otoes and Omahas; held a council with the Pawnees; visited the Cherokees and Creeks and assisted in adjusting the boundaries of their reservations, and made a report proposing locations for the Pottawatomies, Ottawas, Miamis, New York tribes and some others. His report was accepted by the government and he remained with the Indians on their reservations until 1842, when he went to Louisville, Ky., to assume the management of the work of the American Indian Mission Association. Mr. McCoy was the author of a History of Baptist Indian Missions. He died at Louisville in 1846.